10 Natural Substances That Could Help Cure Type 1 Diabetes

Source : greenmedinfo.com



Could the long-sought after cure for type 1 diabetes be as close as your kitchen cupboard? An accumulating body of scientific research appears to point in exactly that direction.

One so-called 'incurable disease' that afflicts millions of people around the world is type 1 diabetes. Unlike type 2 diabetes, where the body becomes resistant to its own insulin, type 1 is characterized by the inability of the body to produce enough insulin, as the beta cells within the pancreas which are responsible for the production of insulin (and the proinsulin from which it is made) are either destroyed or seriously impaired. This can happen due to autoimmune issues, bacterial or viral infections, incompatible foods in the diet and chemical exposures  (or a combination of any one or more of these factors), to name but a few major triggers.
And yet, plenty of peer-reviewed and published research now indicates that plant compounds, including many found within commonly consumed foods, are capable of stimulating beta cell regeneration within the pancreas, and as a result may be potentially provide a cure – truly a four letter word, as far as the profit-based model of medicine goes, which thrives on the concept of the incurability of the disease-afflicted human body in favor of symptom management.

The discovery of the beta cell regenerative potential of various food and compounds is bound to upset a burgeoning diabetes industry, with millions of dollars of public and private money continually being poured into fund-raising efforts for a future "cure"; A cure that will presumably be delivered through the prohibitively expensive pharmaceutical,vaccine or biologic (e.g. stem cells, islet cell xenotransplantation) pipeline, which by the very nature of the FDA drug approval process requires the promotion of synthetic (and therefore patentable) compounds over natural ones.
Let's take a look at the latest preclinical study on the topic, published last month in the Canadian Journal of Physiology and Pharmacology[1]. An active fraction of flaxseed, which researchers named Linun usitassimum active fraction (LU6), was found to generate a wide range of benefits in a type 1 diabetes animal model, including the following:

• Improved glucose utilization in the liver
• Supported normalized glycogenesis (glucose forming activity) in the liver and muscle tissue
• Reduced pancreatic and intestinal glucosidase inhibitory activity, which translates into lower post-meal blood sugar elevations

Even more remarkable was the observation that this flaxseed compound normalized plasma insulin and C-peptide levels (C peptide is not C-reactive protein, rather it is a direct indicator of how much insulin is being produced by the beta cells in the body. Learn more), an indication that beta cell function was effectively restored. The researchers described the truly amazing results as follows:

Normalization of plasma insulin and C-peptide levels were observed in diabetic mice, indicating endogenous insulin secretion after the treatment with LU6. The histochemical and immunohistochemical analysis on pancreatic islets suggests the role of LU6 fraction in islet regeneration and insulin secretion as evident in increase functional pancreatic islets producing insulin. Furthermore, significant insulin producing islet formation was also observed in in vitro PANC-1 cells after LU6 treatment, indicating the cellular aggregates to be newly formed islets. This suggests the potential of LU6 fraction in the formation of new islets in vitro, as well as in vivo. Thus, LU6 can be used as a nutraceutical-based first-line treatment for diabetes. [emphasis added]


Keep in mind that this is not the first time that flaxseed has been found to improve blood sugar disorders. We have a few studies on GreenMedInfo.com already indexed on the topic that you can view here: Flaxseed and Diabetes.
Furthermore, we have found a broad range of natural substances experimentally confirmed to stimulate beta cell regeneration, 10 of  which are listed below:

• Arginine: a 2007 study found that the amino acid L-arginine is capable of stimulating the genesis of beta cells in an animal model of alloxan-induced diabetes.[2]
• Avocado: A 2007 study found that avocado seed extract reduced blood sugar in diabetic rats. Researchers observed a restorative and protective effect on pancreatic islet cells in the treated group.[3]
• Berberine: A 2009 study found that this plant compound, commonly found in herbs such as barberry and goldenseal, induces beta cell regeneration in diabetic rats, which lends explanation for why it has been used for 1400 years in China to treat diabetes.[4]
• Chard: A 2000 study found that chard extract given to diabetic rats stimulates the recovery of injured beta cells.[5]
• Corn Silk: A 2009 study found that corn silk reduces blood sugar and stimulates beta cell regeneration in type 1 diabetic rats.[6]
• Curcumin (from Turmeric): A 2010 study found that curcumin stimulates beta cell regeneration in  type 1 diabetic rats.[7] Additionally, a 2008 study found that curcumin preserves pancreatic islet cell survival and transplantation efficiency.[8]
• Genistein (from soy, red clover): A  2010 study found that genistein induces pancreatic beta-cell proliferation through activation of multiple signaling pathways and prevents insulin-deficient diabetes in mice.[9]
• Honey: A 2010 human study found that long-term consumption of honey might have positive effects on the metabolic derangements of type 1 diabetes, including possible beta cell regeneration as indicating by increases in fasting C-peptide levels.[10]
• Nigella Sativa (black seed): A 2003 animal study found that black seed consumption lead to partial regeneration/proliferation of the beta-cells.[11] A 2010 human study also found that the consumption of one gram of black seed a day for up to 12 weeks had a broad range of beneficial effects in diabetics, including increasing beta cell function.[12]
• Stevia: A 2011 human study found that stevia has anti-diabetic properties, including revitalizing damaged beta cells, and compares favorably with the drug glibenclamide but without the adverse effects

Reduce Sugar

Source : www.helpguide.org

Aside from portion size, perhaps the single biggest problem with the modern Western diet is the amount of added sugar in our food. As well as creating weight problems, too much sugar causes energy spikes and has been linked to diabetes, depression, and even an increase in suicidal behaviors in young people. Reducing the amount of candy and desserts you eat is only part of the solution as sugar is also hidden in foods such as bread, cereals, canned soups and vegetables, pasta sauce, margarine, instant mashed potatoes, frozen dinners, low-fat meals, fast food, and ketchup. Your body gets all it needs from sugar naturally occurring in food so all this added sugar just means a lot of empty calories.

Tips for cutting down on sugar

• Slowly reduce the sugar in your diet a little at a time to give your taste buds time to adjust and wean yourself off the craving.
• Avoid sugary drinks. Try drinking sparkling water with a splash of fruit juice instead.
• Don’t replace saturated fat with sugar. Many of us make the mistake of replacing healthy sources of saturated fat, such as whole milk dairy, with refined carbs or sugary foods, thinking we’re making a healthier choice. Low-fat doesn’t necessarily mean healthy, especially when the fat has been replaced by added sugar to make up for loss of taste.
• Avoid processed or packaged foods like canned soups, frozen dinners, or low-fat meals that often contain hidden sugar that quickly surpasses the recommended limit.
• Be careful when eating out.  Most gravy, dressings and sauces are also packed with salt and sugar, so ask for it to be served on the side.
• Eat healthier snacks.  Cut down on sweet snacks such as candy, chocolate, and cakes. Instead, eat naturally sweet food such as fruit, peppers, or natural peanut butter to satisfy your sweet tooth.
• Check labels and choose low-sugar products.

Do some detective work

Spotting added sugar on food labels can require some sleuthing. Manufacturers are required to provide the total amount of sugar in a serving but do not have to spell out how much of this sugar has been added and how much is naturally in the food. Added sugars must be included on the ingredients list, which is presented in descending order by weight. The trick is deciphering which ingredients are added sugars. They come in a variety of guises. Aside from the obvious ones—sugar, honey, molasses—added sugar can appear as agave nectar, cane crystals, corn sweetener, crystalline fructose, dextrose, evaporated cane juice, fructose, high-fructose corn syrup, invert sugar, lactose, maltose, malt syrup, and more.
A wise approach is to avoid products that have any of these added sugars at or near the top of the list of ingredients—or ones that have several different types of sugar scattered throughout the list. If a product is chock-full of sugar, you would expect to see “sugar” listed first, or maybe second. But food makers can fudge the list by adding sweeteners that aren’t technically called sugar. The trick is that each sweetener is listed separately. The contribution of each added sugar may be small enough that it shows up fourth, fifth, or even further down the list. But add them up and you can get a surprising dose of added sugar.
Let’s take as an example a popular oat-based cereal with almonds whose package boasts that it is “great tasting,” “heart healthy” and “whole grain guaranteed.” Here’s the list of ingredients:

Whole-grain oats, whole-grain wheat, brown sugar, almond pieces, sugar, crisp oats,* corn syrup, barley malt extract, potassium citrate, toasted oats,* salt, malt syrup, wheat bits,* honey, and cinnamon.

*contain sugar, high-fructose corn syrup, honey, and/or brown sugar molasses. 

Combine brown sugar, sugar, corn syrup, barley malt extract, high-fructose corn syrup, honey, brown sugar molasses, and malt syrup, and they add up to a hefty dose of empty calories—more than one-quarter (27%) of this cereal is added sugar, which you might not guess from scanning the ingredient list. This type of calculation can be especially tricky in breakfast cereals, where most of the sugars are added.